李明月，바카라 가라머니 사이트，讲师，医学博士，硕士生导师。2021年6月获得바카라 가라머니 사이트医学博士学位。2021年11月被延边大学聘为“青年图们江学者B类”。现就职于바카라 가라머니 사이트临床药学与药理系，吉林省药学会药理专业委员会委员。近5年主持和参与多项课题，包括国家自然科学基金项目1项，吉林省科技厅项目4项，吉林省教育厅项目1项，延边大学博士科研启动基金1项等。在British journal of pharmacology、Pharmacological research、Journal of ginseng research等国际药学知名期刊上发表SCI论文30余篇。
【联系方式】
0433-2436940；E-mail: myli@ybu.edu.cn
【研究方向】
肿瘤药理、免疫药理、中药药理、药物靶点与活性筛选、药效学研究
【承担科研项目】
1.芒柄花素对葡聚糖硫酸钠诱导的小鼠结肠炎的保护作用（吉林省科技厅项目；项目编号：YDZJ202201ZYTS272； 2022.01-2024.12；项目负责人）
2.松萝酸通过干预上皮-间质转化抑制结直肠癌细胞的增殖、迁移与侵袭的分子机制研究（吉林省教育厅项目；项目编号：JJKH20230641KJ；2023.01-2025.12；项目负责人）
3. 枸杞总黄酮提取物对DSS诱导小鼠结肠炎的改善作用及其机制研究（延边大学博士启动基金；项目编号：ydbq202216；2022.01-2024.12；项目负责人）.
4.ZFP91参与调控经典和非经典炎症小体活化及侧金盏花E干预机制研究（国家自然科学基金；项目编号：81760657； 2018.01-2021.12；项目参与人）.
5.ZFP91通过MAPK信号通路诱导人单核细胞型淋巴瘤THP1细胞分泌IL-1β的研究（吉林省科技创新人才培育计划优秀青年人才基金项目；项目编号：20180520057JH；2018.01-2019.12；项目参与人）.
【代表性论著】
1. Yi Zhong1, Ming Yue Li1, Lizhuo Han, Yi Tai et al. Galangin inhibits programmed cell death-ligand 1 expression by suppressing STAT3 and MYC and enhances T cell tumor-killing activity. Phytomedicine. 116:154877, 2023. (共同第一作者，一区，IF：5.34).
2. Myong Hak Ri1, Ming Yue Li1, Yue Xing, Hong Xiang Zuo et al. Narirutin exerts anti-inflammatory activity by inhibiting NLRP3 inflammasome activation in macrophages. Phytother Res. 2023. (共同第一作者，二区，IF：5.882).
3. Yi zhong, Zhi Hong Zhang, Jing Ying Wang, Yue Xing, Myong Hak Ri, Hong Lan Jin, Hong Xiang Zuo, Ming Yue Li*, Juan Ma*, Xuejun Jin*. Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. Toxicology Letters. 356:75-88, 2022. (共同通讯作者，二区，IF：4.374).
4. Yue Xing, Jing Ying Wang, Ming Yue Li, Zhi Hong Zhang, Hong Lan Jin, Hong Xiang Zuo, Juan Ma* and Xuejun Jin*. Convallatoxin inhibits IL-1β production by suppressing zinc finger protein 91-mediated pro-IL-1β ubiquitination and caspase-8 inflammasome activity. Br J Pharmacol.2022 (一区，Top，IF：9.473).
5. Zhi Hong Zhang1, Ming Yue Li1, Zhe Wang, Hong Xiang Zuo, Jing Ying Wang, Yue Xing, Chenghua Jin, Guanghua Xu, Lianxun Piao, Hongxin Piao, Juan Ma*, Xuejun Jin*. Convallatoxin promotes apoptosis and inhibits proliferation and angiogenesis through crosstalk between JAK2/STAT3 (T705) and mTOR/STAT3 (S727) signaling pathways in colorectal cancer. Phytomedicine. 68:153172, 2020. (共同第一作者，二区，IF：5.882).
6. Ming Yue Li, Zhi Hong Zhang, Zhe Wang, Hong Xiang Zuo, Jing Ying Wang, Yue Xing, Cheng Hua Jin, Guang Hua Xu, Lian Xun Piao, Juan Ma*, Xuejun Jin*. Convallatoxin protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB signaling through activation of PPARγ. Pharmacological Research.147:104355, 2019. (第一作者，一区，IF：7.658).
7. Chunliu Mi, Zhe Wang, Ming Yue Li, Zhi Hong Zhang, Juan Ma and Xuejun Jin. Zinc finger protein 91 positively regulates the production of IL-1β in macrophages by activation of MAPKs and non-canonical caspase-8 inflammasome. British Journal of Pharmacology. 175:4338–4352, 2018 (一区，Top，IF：9.473).
8. Ming-Yue Li, Chunliu Mi, Ke Si Wang, Zhe Wang, Hong Xiang Zuo, Lian Xun Piao, Guang Hua Xu, Xuezheng Li, Juan Ma*, Xuejun Jin*. Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1 a signaling. Chemico-Biological Interactions. 274:58-67,2017. (第一作者，二区，IF：5.194)
